Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
| Phenotype | Phenotype.cls#treated_versus_cont_repos |
| Upregulated in class | cont |
| GeneSet | GO|GO:0007422 |
| Enrichment Score (ES) | -0.7366087 |
| Normalized Enrichment Score (NES) | -1.5930818 |
| Nominal p-value | 0.017492712 |
| FDR q-value | 0.2794316 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 430 | ASCL2 (achaete-scute complex homolog 2 (Drosophila)) | 727 | 47.937 | 0.0296 | No | ||
| 2 | 23405 | "DICER1 (dicer 1, ribonuclease type III)" | 995 | 37.181 | 0.0671 | No | ||
| 3 | 4763 | NF1 (neurofibromin 1) | 1656 | 23.147 | 0.0662 | No | ||
| 4 | 224 | "ALDH3A2 (aldehyde dehydrogenase 3 family, member A2)" | 3134 | 10.261 | 0.0074 | No | ||
| 5 | 2676 | GFRA3 (GDNF family receptor alpha 3) | 3407 | 9.134 | 0.0065 | No | ||
| 6 | 861 | RUNX1 (runt-related transcription factor 1) | 3672 | 8.086 | 0.0045 | No | ||
| 7 | 6647 | "SOD1 (superoxide dismutase 1, soluble)" | 3814 | 7.463 | 0.0077 | No | ||
| 8 | 9639 | ARHGEF10 (Rho guanine nucleotide exchange factor (GEF) 10) | 4709 | 4.696 | -0.0299 | No | ||
| 9 | 50674 | NEUROG3 (neurogenin 3) | 5010 | 4.014 | -0.0392 | No | ||
| 10 | 864 | RUNX3 (runt-related transcription factor 3) | 5809 | 2.608 | -0.0750 | No | ||
| 11 | 5274 | "SERPINI1 (serpin peptidase inhibitor, clade I (neuroserpin), member 1)" | 5888 | 2.509 | -0.0754 | No | ||
| 12 | 2304 | FOXE1 (forkhead box E1 (thyroid transcription factor 2)) | 6721 | 1.577 | -0.1143 | No | ||
| 13 | 2298 | FOXD4 (forkhead box D4) | 7402 | 1.065 | -0.1463 | No | ||
| 14 | 30812 | SOX8 (SRY (sex determining region Y)-box 8) | 8253 | 0.631 | -0.1874 | No | ||
| 15 | 2115 | ETV1 (ets variant gene 1) | 8280 | 0.621 | -0.1878 | No | ||
| 16 | 2306 | FOXD2 (forkhead box D2) | 9540 | 0.245 | -0.2495 | No | ||
| 17 | 3670 | ISL1 (ISL LIM homeobox 1) | 10817 | -0.051 | -0.3123 | No | ||
| 18 | 1959 | "EGR2 (early growth response 2 (Krox-20 homolog, Drosophila))" | 11293 | -0.162 | -0.3355 | No | ||
| 19 | 5457 | POU4F1 (POU class 4 homeobox 1) | 12937 | -0.587 | -0.4157 | No | ||
| 20 | 64843 | ISL2 (ISL LIM homeobox 2) | 12955 | -0.592 | -0.4157 | No | ||
| 21 | 7368 | UGT8 (UDP glycosyltransferase 8) | 13121 | -0.644 | -0.4230 | No | ||
| 22 | 200350 | FOXD4L1 (forkhead box D4-like 1) | 13158 | -0.654 | -0.4238 | No | ||
| 23 | 6334 | "SCN8A (sodium channel, voltage gated, type VIII, alpha subunit)" | 13190 | -0.664 | -0.4245 | No | ||
| 24 | 2668 | GDNF (glial cell derived neurotrophic factor) | 14268 | -1.116 | -0.4760 | No | ||
| 25 | 40 | "ACCN1 (amiloride-sensitive cation channel 1, neuronal)" | 14585 | -1.287 | -0.4898 | No | ||
| 26 | 23114 | NFASC (neurofascin homolog (chicken)) | 14635 | -1.320 | -0.4904 | No | ||
| 27 | 2301 | FOXE3 (forkhead box E3) | 14731 | -1.384 | -0.4932 | No | ||
| 28 | 27022 | FOXD3 (forkhead box D3) | 15423 | -1.891 | -0.5247 | No | ||
| 29 | 575 | BAI1 (brain-specific angiogenesis inhibitor 1) | 15740 | -2.196 | -0.5373 | No | ||
| 30 | 2297 | FOXD1 (forkhead box D1) | 16037 | -2.548 | -0.5484 | No | ||
| 31 | 6497 | SKI (v-ski sarcoma viral oncogene homolog (avian)) | 18818 | -14.221 | -0.6660 | Yes | ||
| 32 | 5376 | PMP22 (peripheral myelin protein 22) | 20252 | -152.900 | -0.5280 | Yes | ||
| 33 | 2947 | GSTM3 (glutathione S-transferase M3 (brain)) | 20280 | -185.916 | -0.2757 | Yes | ||
| 34 | 2065 | ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)) | 20296 | -203.653 | 0.0014 | Yes |
